Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.30 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738406 | 0.77 | NR1H2 (0.40) | ALDH1A1ACACBMME | |
| SCHEMBL7738440 | 0.75 | TACR1 (0.46) | KDM4EALDH1A1TACR1 | |
| SCHEMBL7738442 | 0.75 | TACR1 (0.46) | KDM4EALDH1A1TACR1 | |
| SCHEMBL7738432 | 0.70 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL8293498 | 0.70 | — | — | |
| SCHEMBL7736591 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL7736594 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL7739191 | 0.68 | NR1H2 (0.39) | ALDH1A1 | |
| SCHEMBL7739187 | 0.66 | NR1H2 (0.39) | ALDH1A1ACACB | |
| SCHEMBL7739198 | 0.66 | NR1H2 (0.39) | ALDH1A1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |