SCHEMBL8388153

SCHEMBL8388153

CCCCCCCCCCCCCCCCCCc1ccc(C(=O)CBr)cc1

nearest known ligand 0.77

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRA P10827 12/20 0.77
THRB P10828 12/20 0.77
HAO1 Q9UJM8 1/20 0.65
RARB P10826 5/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ALDH1A1 P00352 1/20 0.61
RARA P10276 1/20 0.61
MAPT P10636 1/20 0.61
MTOR P42345 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15174539 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL15186439 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL8984157 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL7736637 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL3929949 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL8984247 1.00 THRA (0.77) THRATHRBHAO1RARBMEN1
SCHEMBL638654 0.98 THRA (0.73) THRATHRBHAO1RARBMEN1
SCHEMBL11110027 0.95 THRA (0.70) THRATHRBHAO1RARBMEN1
SCHEMBL3011724 0.93 THRA (0.66) THRATHRBHAO1RARBALDH1A1
SCHEMBL8205823 0.88 RARB (0.68) THRATHRBHAO1RARBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0803083-B1 IMAGE-RECORDING MATERIALS POLAROID CORP (US) 1999-04-21 EP disclosed
EP-0803083-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1997-10-29 EP disclosed
US-5674986-A FOR HEAT-DEVELOPABLE PHOTOSENSITIVE IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1997-10-07 US disclosed
WO-1997018497-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1997-05-22 WO disclosed
US-5569574-A CONTAINING CYCLIC 1,3-SULFUR-OXYGEN MOIETY; DIFFUSION TRANSFER PROCESSES POLAROID CORPORATION (US) 1996-10-29 US disclosed