Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837558 | 0.86 | PTPN1 (0.42) | HDAC1ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL7539805 | 0.85 | NPC1 (0.42) | ALDH1A1LMNAHTTKMT2AHPGD | |
| SCHEMBL7701621 | 0.85 | HDAC1 (0.36) | HDAC1ALDH1A1KDM4ELMNAGLA | |
| SCHEMBL7539969 | 0.84 | DRD4 (0.44) | ALDH1A1KDM4EKMT2AHPGDBCHE | |
| SCHEMBL7535029 | 0.84 | GAA (0.42) | ALDH1A1KDM4ELMNAKMT2AHPGD | |
| SCHEMBL7558300 | 0.82 | KMT2A (0.42) | ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL7556319 | 0.82 | HTR4 (0.40) | ALDH1A1KDM4ELMNAKMT2ABCHE | |
| SCHEMBL7562697 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL5846085 | 0.80 | BCHE (0.41) | HDAC1ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL5846091 | 0.80 | BCHE (0.41) | HDAC1ALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410556-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | disclosed |