Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7736339 | 0.88 | LMNA (0.41) | NISCHPTGS2MGAMGAASI | |
| Hydrochloric Acid SCHEMBL7736802 | 0.88 | NISCH (0.58) | NISCHMAOAMAOBMAPK13MAPK12 | |
| SCHEMBL7736799 | 0.84 | NISCH (0.45) | NISCHMAOAMAOBMAPK13MAPK12 | |
| SCHEMBL6826340 | 0.83 | PTGS2 (0.50) | NISCHMAOAMAOBMAPK13MAPK12 | |
| SCHEMBL7727522 | 0.82 | MAP2 (0.46) | NISCHMAOAMAOBPTGS2MAP2 | |
| SCHEMBL6824458 | 0.81 | NISCH (0.56) | NISCHMAOAMAOBPTGS2 | |
| Hydrochloric Acid SCHEMBL7735661 | 0.81 | NISCH (0.55) | NISCHMAOAMAOBPTGS2 | |
| SCHEMBL6824069 | 0.80 | NISCH (0.58) | NISCHMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6820932 | 0.80 | PTGS2 (0.52) | NISCHPTGS2MAP2 | |
| SCHEMBL6824382 | 0.79 | NISCH (0.54) | NISCHMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410562-B1 | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY | 2002-06-25 | — | — | US | disclosed |