Sugi Predict

Sugi Predict / Compounds / SCHEMBL7736932

SCHEMBL7736932

SCHEMBL7736932

O=C(Nc1ccccc1)NC1C(=O)N(CC2C3CC4CC(C3)CC2C4)c2ccccc2N(c2ccccc2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 20/20 1.00
▸ CCKAR P32238 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8637815 0.87 CCKBR (0.76) CCKBRCCKAR
SCHEMBL8897733 0.86 CCKBR (0.76) CCKBRCCKAR
SCHEMBL8622444 0.84 CCKBR (0.73) CCKBRCCKAR
SCHEMBL7375453 0.82 CCKBR (1.00) CCKBR
SCHEMBL8635148 0.82 CCKBR (0.69) CCKBRCCKAR
Dimethylamine SCHEMBL8639336 0.80 CCKBR (0.94) CCKBRCCKAR
SCHEMBL8641287 0.79 CCKBR (1.00) CCKBRCCKAR
Dimethylamine SCHEMBL8638834 0.79 CCKBR (0.94) CCKBR
SCHEMBL8636911 0.79 CCKBR (1.00) CCKBRCCKAR
SCHEMBL8635376 0.78 CCKBR (1.00) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413930-B1 CONTROLLING EYE MOVEMENT GLAXO WELLCOME SPA (IT) 2002-07-02 — — US disclosed
EP-0558104-B1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO WELLCOME SPA (IT) 1998-07-29 — — EP disclosed
US-5637697-A ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ GLAXO SPA (IT) 1997-06-10 — — US disclosed
US-5580895-A GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS GLAXO SPA (IT) 1996-12-03 — — US disclosed
EP-0558104-A1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO S.p.A. (IT) 1993-09-01 — — EP disclosed