Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280367 | 0.85 | NPC1 (0.38) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL25409885 | 0.84 | NPC1 (0.36) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7736252 | 0.83 | NPC1 (0.36) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5276856 | 0.83 | NPC1 (0.37) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6535795 | 0.82 | NPC1 (0.48) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8082025 | 0.82 | NPC1 (0.34) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5274123 | 0.81 | NPC1 (0.36) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6753077 | 0.80 | NPC1 (0.34) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL20363907 | 0.79 | NPC1 (0.47) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4444920 | 0.78 | NPC1 (0.46) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |