Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737089 | 0.86 | PTGIR (0.43) | PTGIRPTGER1PTGER3PTGDRHRH3 | |
| SCHEMBL7737680 | 0.85 | PTGIR (0.46) | PTGIRPTGER1PTGER3PTGDRHRH3 | |
| SCHEMBL7737683 | 0.83 | HRH3 (0.43) | PTGIRPTGER1PTGER3PTGDRHRH3 | |
| SCHEMBL7730243 | 0.82 | HRH3 (0.43) | PTGIRPTGER1PTGER3PTGDRHRH3 | |
| SCHEMBL7736442 | 0.80 | PTGIR (0.62) | PTGIRPTGER1PTGER3PTGDRALDH1A1 | |
| SCHEMBL7737082 | 0.79 | HRH3 (0.46) | PTGIRHRH3ALDH1A1KMT2AKDM4E | |
| SCHEMBL7737197 | 0.78 | PTGIR (0.45) | PTGIRHRH3ALDH1A1PKM | |
| SCHEMBL7736474 | 0.77 | PPARD (0.44) | PTGIRHRH3ALDH1A1KMT2APKM | |
| SCHEMBL7737231 | 0.77 | PTGIR (0.56) | PTGIRHRH3 | |
| SCHEMBL7739673 | 0.76 | GRM7 (0.44) | PTGIRHRH3ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |