SCHEMBL7737404

SCHEMBL7737404

Cc1cc(C)c(S(=O)(=O)S(=O)(=O)C(Br)(Br)Br)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45
RAPGEF4 Q8WZA2 6/20 0.44
F2 P00734 3/20 0.41
PRSS1 P07477 3/20 0.41
PRSS2 P07478 3/20 0.41
PRSS3 P35030 3/20 0.41
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 2/20 0.39
GAA P10253 2/20 0.37
TSHR P16473 2/20 0.37
POLB P06746 1/20 0.37
GFER P55789 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21117641 0.81 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL29256032 0.73 CA1 (0.54) CA1CA2MMP1MMP2MMP9
SCHEMBL2047218 0.71 RAPGEF4 (0.67) CA1CA2MMP1MMP2MMP9
SCHEMBL330754 0.69 CA1 (0.54) CA1CA2MMP1MMP2MMP9
SCHEMBL8271353 0.69 CA1 (0.54) CA1CA2MMP1MMP2MMP9
SCHEMBL14454650 0.68 RAPGEF4 (0.52) CA1CA2MMP1MMP2MMP9
SCHEMBL10050619 0.68 L3MBTL1 (0.55) CA1CA2MMP1MMP2MMP9
SCHEMBL5490404 0.67 RAPGEF4 (0.70) CA1CA2MMP1MMP2MMP9
SCHEMBL10846507 0.67 CA1 (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL16140106 0.67 CA1 (0.52) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391536-B2 MIXTURE OF AN ORGANIC SILVER SALT, REDUCING AGENT AND BINDER FUJI PHOTO FILM CO., LTD. (JP) 2002-05-21 US disclosed
US-20010023049-A1 Thermally processed image recording material FUJIFILM CORPORATION (JP) 2001-09-20 US disclosed