Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288952 | 0.85 | MAOA (0.48) | MAOAMAOBKMT2AMEN1CYP1A2 | |
| SCHEMBL5233047 | 0.83 | MAOA (0.61) | MAOAMAOBTP53CYP1A2CYP3A4 | |
| SCHEMBL28866669 | 0.82 | — | — | |
| SCHEMBL19235947 | 0.82 | — | — | |
| SCHEMBL152134 | 0.81 | — | — | |
| SCHEMBL31271806 | 0.81 | MAOA (0.54) | MAOAMAOBKMT2AMEN1CYP1A2 | |
| SCHEMBL2423250 | 0.80 | — | — | |
| SCHEMBL30358603 | 0.78 | MAOA (0.57) | MAOAMAOBKMT2ASOAT1MEN1 | |
| SCHEMBL22344277 | 0.78 | MAOA (0.52) | MAOAMAOBKMT2AMEN1CYP1A2 | |
| Milacemide SCHEMBL194513 | 0.78 | MAOA (0.63) | MAOAMAOBKMT2ASOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414140-B2 | BY USE OF WITTIG REACTION IN WHICH WEAK BASES ARE USED | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-07-02 | — | — | US | disclosed |