Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739367 | 0.90 | MCL1 (0.32) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL7729398 | 0.89 | NPC1 (0.36) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL7736905 | 0.83 | NPC1 (0.32) | NPC1RAB9ARXFP1TP53MAPT | |
| SCHEMBL7736862 | 0.81 | TLR8 (0.33) | NPC1RAB9ARXFP1TP53MAPT | |
| SCHEMBL7568491 | 0.81 | NPC1 (0.37) | NPC1RAB9ARXFP1TP53MAPT | |
| SCHEMBL7737484 | 0.81 | POLB (0.33) | NPC1RAB9ARXFP1 | |
| SCHEMBL28908795 | 0.79 | TLR8 (0.31) | — | |
| SCHEMBL7030783 | 0.77 | NPC1 (0.42) | NPC1RAB9ATP53MAPTKDM4E | |
| SCHEMBL7736252 | 0.76 | NPC1 (0.36) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL20694832 | 0.76 | BACE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414100-B1 | COMPOUND HAVING EXTREMELY LOW VAPOR PRESSURE AND HIGH DECOMPOSITION TEMPERATURE; CROSSLINKING AGENT FOR WEATHER RESISTANT POLYMERS | OTSUKA CHEMICAL CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1055669-A1 | BISBENZOTRIAZOLYLPHENOL COMPOUNDS, ULTRAVIOLET ABSORBER, ULTRAVIOLET-ABSORBING POLYMER, AND RESIN COMPOSITION AND COATING MATERIAL BOTH CONTAINING THESE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2000-11-29 | — | — | EP | disclosed |