Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564694 | 0.87 | NPC1 (0.35) | NPC1RAB9A | |
| SCHEMBL7566053 | 0.87 | NPC1 (0.44) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL75316 | 0.82 | NPC1 (0.36) | NPC1RAB9AHIF1ACYP2C9CYP2C19 | |
| SCHEMBL27623464 | 0.82 | RAB9A (0.42) | NPC1RAB9AHIF1ACYP2C9CYP2C19 | |
| SCHEMBL7737494 | 0.81 | NPC1 (0.31) | NPC1RAB9ARXFP1MAPTTP53 | |
| SCHEMBL27929913 | 0.81 | NPC1 (0.36) | NPC1RAB9ARXFP1MAPTTP53 | |
| SCHEMBL15910157 | 0.80 | NPC1 (0.55) | NPC1RAB9AHIF1ACYP2C9CYP2C19 | |
| SCHEMBL74862 | 0.80 | NPC1 (0.35) | NPC1RAB9AHIF1ACYP2C9CYP2C19 | |
| SCHEMBL195720 | 0.80 | NPC1 (0.36) | NPC1RAB9ARXFP1MAPTTP53 | |
| SCHEMBL29400095 | 0.80 | NPC1 (0.36) | NPC1RAB9ARXFP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | claimed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |