Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133316 | 1.00 | PTGS2 (0.66) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL2782853 | 0.98 | PTGS2 (0.68) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL1681771 | 0.95 | PTGS2 (0.65) | PTGS2MAPK14PTGS1BCAT2 | |
| Ammonia Solution, Strong SCHEMBL28994523 | 0.93 | PTGS2 (0.62) | PTGS2MAPK14PTGS1BCAT2 | |
| Hydrogen Sulfide SCHEMBL27804205 | 0.93 | PTGS2 (0.62) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL27961786 | 0.88 | PTGS2 (0.58) | PTGS2MAPK14PTGS1 | |
| Thiophene SCHEMBL8678681 | 0.87 | PTGS2 (0.57) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL12270183 | 0.86 | PTGS2 (0.56) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL12270289 | 0.86 | PTGS2 (0.56) | PTGS2MAPK14PTGS1BCAT2 | |
| SCHEMBL27876136 | 0.84 | PTGS2 (0.54) | PTGS2MAPK14PTGS1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214630-A2 | MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001007506-A2 | MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2001-02-01 | — | — | WO | disclosed |