SCHEMBL7738101

SCHEMBL7738101

CN(C)c1ccc(/C=N\C=C\N=C/c2ccccc2O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
ALDH1A1 P00352 6/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
GAA P10253 3/20 0.47
HTT P42858 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
THRB P10828 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 4/20 0.45
MAPK1 P28482 1/20 0.44
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
CYBB P04839 1/20 0.42
NOX4 Q9NPH5 1/20 0.42
LMNA P02545 2/20 0.41
CA12 O43570 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811525 0.84 MAPT (0.65) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL7022851 0.84 CA12 (0.65) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL5528283 0.80 CA12 (0.59) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL8511457 0.80 CA12 (0.59) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL6811190 0.78 L3MBTL1 (0.69) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL6811193 0.78 L3MBTL1 (0.69) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL11215737 0.78 CA12 (0.57) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL11503328 0.78 CA12 (0.57) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL6745561 0.77 MAPT (0.51) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL6743499 0.77 MAPT (0.42) MAPTALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413926-B2 PREVENTION REDEPOSITING OF MIGRANT DYES DURING WASHING CIBA SPECIALTY CHEMICALS CORPORATION 2002-07-02 US disclosed
US-20010023238-A1 Process for treating textile materials CIBA SPECIALTY CHEMICALS CORP. 2001-09-20 US disclosed