SCHEMBL6745561

SCHEMBL6745561

CCN(C)c1ccc(/C=N\C=C\N=C/c2ccc(N(C)CC)cc2O)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 16/20 0.51
ALDH1A1 P00352 15/20 0.51
KDM4E B2RXH2 10/20 0.51
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
LMNA P02545 6/20 0.51
TDP1 Q9NUW8 3/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
GAA P10253 8/20 0.51
HTT P42858 4/20 0.51
THRB P10828 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
SMN1; SMN2 Q16637 6/20 0.49
BLM P54132 1/20 0.48
MAPK1 P28482 1/20 0.48
HPGD P15428 5/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
ALOX12 P18054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6745565 0.84 ALDH1A1 (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL6811487 0.81 MAPT (0.62) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL6811525 0.80 MAPT (0.65) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL5729223 0.79 TYR (0.46) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL6743499 0.78 MAPT (0.42) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL7794628 0.77 L3MBTL1 (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL6744740 0.77 MAPT (0.45) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL7794635 0.77 L3MBTL1 (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL6744744 0.77 MAPT (0.45) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL7738101 0.77 MAPT (0.56) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689733-B1 ENHANCING ACTION OF PEROXY COMPOUNDS; WASHING, CLEANING, DISINFECTING CIBA SPECIALTY CHEMICALS CORPORATION 2004-02-10 US disclosed
EP-1159259-A1 MANGANESE COMPLEXES OF SALEN LIGANDS AND THE USE THEREOF Ciba SC Holding AG (CH) 2001-12-05 EP disclosed
WO-2000053574-A1 MANGANESE COMPLEXES OF SALEN LIGANDS AND THE USE THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-14 WO disclosed