Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963 | 0.91 | TSHR (0.52) | TSHRTHRBGALR3MAPTBLM | |
| SCHEMBL4593744 | 0.89 | THRB (0.52) | TSHRTHRBGALR3MAPTBLM | |
| Propane SCHEMBL8440363 | 0.87 | THRB (0.50) | TSHRTHRBGALR3MAPTBLM | |
| SCHEMBL4640880 | 0.86 | TSHR (0.56) | TSHRTHRBGALR3MAPTBLM | |
| SCHEMBL23573051 | 0.84 | TSHR (0.59) | TSHRTHRBGALR3MAPTBLM | |
| SCHEMBL554544 | 0.83 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL9769623 | 0.83 | THRB (0.48) | TSHRTHRBGALR3MAPTBLM | |
| 1,4-Butanediol SCHEMBL1225181 | 0.83 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL11684183 | 0.83 | TSHR (0.44) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL27847758 | 0.83 | TSHR (0.44) | TSHRTHRBSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059968-A9 | GRAFT, GRAFT-BLOCK, BLOCK-GRAFT, AND STAR-SHAPED COPOLYMERS AND METHODS OF MAKING THEM | UNIV NEW YORK STATE RES FOUND (US) | 2002-02-21 | — | — | WO | claimed |