SCHEMBL7738434

SCHEMBL7738434

Oc1ccc2cccc(O)c2n1.[GaH3]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.61
PLAU P00749 1/20 0.61
NCF1 P14598 1/20 0.61
ALOX12 P18054 3/20 0.59
ALDH1A1 P00352 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
HIF1A Q16665 1/20 0.59
HSD17B10 Q99714 1/20 0.59
KMT2A Q03164 7/20 0.55
KDM4E B2RXH2 6/20 0.55
SOS2 Q07890 1/20 0.55
TSHR P16473 2/20 0.54
MMP2 P08253 1/20 0.54
CHRM1 P11229 1/20 0.54
COMT P21964 1/20 0.54
ADRA1A P35348 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15442576 1.00 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL30082244 0.98 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL672744 0.98 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
Ammonia Solution, Strong SCHEMBL3284067 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL6540982 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL1496246 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL8467827 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL16444064 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL413180 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL973003 0.95 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020034657-A1 Organic electroluminescence device NEC CORPORATION. 2002-03-21 US disclosed