Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AGXT | P21549 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28327424 | 0.98 | CHRM2 (0.60) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL1134127 | 0.86 | CHRM2 (0.74) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| Hydrochloric Acid SCHEMBL6122475 | 0.84 | CHRM2 (0.72) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL27962852 | 0.84 | CHRM2 (0.62) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL29370584 | 0.84 | CHRM2 (0.68) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL297410 | 0.84 | CHRM2 (0.68) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL18685365 | 0.84 | CHRM2 (0.62) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL7917100 | 0.82 | CHRM2 (0.60) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| Hydrochloric Acid SCHEMBL4421884 | 0.82 | CHRM2 (0.60) | CHRM2ALDH1A1HTTSMN1; SMN2MMP13 | |
| SCHEMBL4916089 | 0.82 | CHRM2 (0.81) | CHRM2ALDH1A1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410700-B1 | Glycan derivatives | MACQUARIE RESEARCH LTD. (AU) | 2002-06-25 | — | — | US | claimed |
| EP-1021455-A1 | GLYCAN DERIVATIVES | Macquarie Research Ltd. (AU) | 2000-07-26 | — | — | EP | claimed |
| EP-1021455-A4 | GLYCAN DERIVATIVES | MACQUARIE RES LTD (AU) | 2000-07-26 | — | — | EP | claimed |
| WO-1998015566-A1 | GLYCAN DERIVATIVES | MACQUARIE RESEARCH LTD. (AU) | 1998-04-16 | — | — | WO | claimed |
| US-9616064-B2 | Rho kinase inhibitors and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20140179689-A1 | NOVEL RHO KINASE INHIBITORS AND METHODS OF USE | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-6410700-B1 | Glycan derivatives | MACQUARIE RESEARCH LTD. (AU) | 2002-06-25 | — | — | US | disclosed |
| EP-1021455-A1 | GLYCAN DERIVATIVES | Macquarie Research Ltd. (AU) | 2000-07-26 | — | — | EP | disclosed |
| EP-1021455-A4 | GLYCAN DERIVATIVES | MACQUARIE RES LTD (AU) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015566-A1 | GLYCAN DERIVATIVES | MACQUARIE RESEARCH LTD. (AU) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179689-A1 | NOVEL RHO KINASE INHIBITORS AND METHODS OF USE | ROCK1, ROCK2, RHOA | CHRM2 1966/4885ALDH1A1 3573/4885HTT 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.