Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 10/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417405 | 0.84 | HSD17B1 (0.73) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL14417354 | 0.83 | HSD17B1 (0.70) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL29291203 | 0.83 | CYP1A2 (0.53) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL1402219 | 0.83 | CYP1A2 (0.63) | CYP1A2HSD17B1HSD17B2PLAUKDM4E | |
| SCHEMBL12722493 | 0.80 | HSD17B1 (0.49) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL14417221 | 0.79 | HSD17B1 (0.70) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| P-Cresol SCHEMBL5528682 | 0.79 | HSD17B1 (0.56) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL16632676 | 0.79 | CYP1A2 (0.49) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL444105 | 0.77 | HSD17B1 (0.84) | CYP1A2HSD17B1HSD17B2PLAUESR1 | |
| SCHEMBL15451 | 0.77 | HSD17B1 (0.70) | CYP1A2HSD17B1HSD17B2PLAUESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521317-B | Sulfonated naphthol bola type surfactant for oil displacement of heavy oil reservoir as well as synthetic method and application thereof | 甘肃智仑新材料科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| US-7211414-B2 | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity | VISIGEN BIOTECHNOLOGIES, INC. (US) | 2007-05-01 | — | — | US | claimed |
| CN-117865925-A | 3, 4-benzocoumarin compound based on complex functional aromatic hydrocarbon and preparation method and application thereof | 上海瑞苷生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4153555-B1 | PHOTOOXIDATION OF PHENOLIC COMPOUNDS | DSM IP ASSETS BV (NL) | 2024-01-31 | — | — | EP | disclosed |
| EP-3415641-B1 | METHOD FOR ANALYSIS OF MOLECULES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-4153555-A1 | PHOTOOXIDATION OF PHENOLIC COMPOUNDS | DSM IP Assets B.V. (NL) | 2023-03-29 | — | — | EP | disclosed |
| CN-115667201-A | Photooxidation of phenolic compounds | 帝斯曼知识产权资产管理有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-11492358-B1 | Macrocyclic indole derivatives | THE BROAD INSTITUTE, INC. (US) | 2022-11-08 | — | — | US | disclosed |
| CN-112521317-B | Sulfonated naphthol bola type surfactant for oil displacement of heavy oil reservoir as well as synthetic method and application thereof | 甘肃智仑新材料科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |
| US-5886014-A | TREATMENT AND/OR PROPHYLAXIS OF A VARIETY OF DISORDERS, INCLUDING HYPERLIPEMIA, HYPERGLYCEMIA, OBESITY, IMPAIRED GLUCOSE TOLERANCE (IGT), INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0745600-A1 | Benzimidazole derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| US-4772742-A | POLYESTER INTERMEDIATES | AMOCO CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4709080-A | POLYESTERS | STANDARD OIL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492358-B1 | Macrocyclic indole derivatives | CCND2, CCNT2, IDO1 | CYP1A2 226/4885HSD17B1 1940/4885HSD17B2 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.