P-Cresol

P-Cresol

SCHEMBL5528682

Cc1ccc(O)cc1.Oc1cccc2cc(Cl)ccc12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 7/20 0.56
HSD17B2 P37059 7/20 0.56
ESR1 P03372 5/20 0.56
ESR2 Q92731 5/20 0.56
PLAU P00749 1/20 0.46
PYGL P06737 1/20 0.44
CYP1A2 P05177 3/20 0.44
CYP2C19 P33261 1/20 0.44
ACHE P22303 1/20 0.42
TLR8 Q9NR97 1/20 0.40
TRPV1 Q8NER1 1/20 0.39
NQO2 P16083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL772927 0.86 HSD17B1 (0.59) HSD17B1HSD17B2ESR1ESR2PLAU
1-Naphthol SCHEMBL7997314 0.79 CYP1A2 (0.68) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL773863 0.79 CYP1A2 (0.63) HSD17B1HSD17B2ESR1ESR2PLAU
Parachlorophenol SCHEMBL5534621 0.77 HSD17B1 (0.56) HSD17B1HSD17B2ESR1ESR2PLAU
SCHEMBL14417405 0.76 HSD17B1 (0.73) HSD17B1HSD17B2ESR1ESR2PLAU
SCHEMBL15451 0.74 HSD17B1 (0.70) HSD17B1HSD17B2ESR1ESR2PLAU
SCHEMBL29364213 0.74 HSD17B1 (0.70) HSD17B1HSD17B2ESR1ESR2PLAU
SCHEMBL29738652 0.74 HSD17B1 (0.70) HSD17B1HSD17B2ESR1ESR2PLAU
1-Naphthol SCHEMBL6742778 0.74 CYP1A2 (0.69) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL29291190 0.73 TLR8 (0.53) HSD17B1HSD17B2ESR1ESR2TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844328-A2 USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING Pacific Biosciences of California, Inc. (US) 2007-10-17 EP disclosed
EP-1790202-A2 APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES Pacific Biosciences of California, Inc. (US) 2007-05-30 EP disclosed
WO-2006083751-A2 USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2006-08-10 WO disclosed
WO-2006044078-A2 APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2006-04-27 WO disclosed