Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18477945 | 0.89 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1SMN1; SMN2GAANPC1 | |
| SCHEMBL1123143 | 0.88 | RXRA (0.72) | SMN1; SMN2HRH3RXRARXRBNPC1 | |
| SCHEMBL1123094 | 0.85 | NPC1 (0.70) | ALDH1A1HTTSMN1; SMN2HRH3RXRA | |
| SCHEMBL967078 | 0.85 | HSD17B10 (0.67) | ALDH1A1MAPT | |
| SCHEMBL10789890 | 0.84 | RXRA (0.70) | ALDH1A1SMN1; SMN2RXRARXRBNPC1 | |
| SCHEMBL18521456 | 0.82 | RARB (0.68) | ALDH1A1SMN1; SMN2RXRARXRBNPC1 | |
| SCHEMBL11358158 | 0.82 | RARB (0.68) | ALDH1A1SMN1; SMN2RXRARXRBNPC1 | |
| SCHEMBL18521452 | 0.82 | RARB (0.68) | ALDH1A1SMN1; SMN2RXRARXRBNPC1 | |
| SCHEMBL9815726 | 0.82 | SLC6A2 (0.61) | ALDH1A1SMN1; SMN2HRH3LMNA | |
| SCHEMBL4324090 | 0.82 | MAPT (0.53) | L3MBTL1SMN1; SMN2NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |