Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.60 |
| ▸ | RARA | P10276 | 2/20 | 0.60 |
| ▸ | RARG | P13631 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550099 | 0.96 | RARB (0.59) | RARBRARARARGMCL1PPARA | |
| SCHEMBL7736771 | 0.87 | RARB (0.78) | RARBRARARARGMCL1 | |
| SCHEMBL9238571 | 0.85 | RARB (0.76) | RARBRARARARGPPARAPPARG | |
| SCHEMBL5398835 | 0.84 | KAT8 (0.51) | RARBRARARARGMCL1PPARA | |
| SCHEMBL16684105 | 0.84 | MAOB (0.51) | RARBRARARARGMCL1PPARA | |
| SCHEMBL3281472 | 0.83 | RARB (0.78) | RARBRARARARGPPARAPPARG | |
| SCHEMBL3281551 | 0.83 | RARB (0.78) | RARBRARARARGPPARAPPARG | |
| SCHEMBL28260247 | 0.83 | RARB (0.78) | RARBRARARARGPPARAPPARG | |
| SCHEMBL7730338 | 0.83 | RARB (0.51) | RARBRARARARGMCL1PPARA | |
| SCHEMBL29893781 | 0.83 | DGAT1 (0.51) | RARBRARARARGMCL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468606-B1 | LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE | CHISSO CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0808825-B1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORP (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5922243-A | LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY | CHISSO CORPORATION (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0808825-A1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1997-11-26 | — | — | EP | disclosed |