Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | MPL | P40238 | 4/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730650 | 0.91 | RARB (0.55) | RARBRARARARGMCL1LTB4R2 | |
| SCHEMBL7738951 | 0.83 | RARB (0.60) | RARBRARARARGMCL1PPARG | |
| SCHEMBL7730341 | 0.81 | RARB (0.45) | RARBRARARARGMCL1LTB4R2 | |
| SCHEMBL9842588 | 0.81 | RARB (0.63) | RARBRARARARGMCL1PPARG | |
| SCHEMBL9509918 | 0.81 | METAP2 (0.53) | MCL1LTB4R2BRS3PPARGMETAP2 | |
| SCHEMBL6550099 | 0.80 | RARB (0.59) | RARBRARARARGMCL1PPARG | |
| SCHEMBL9755592 | 0.80 | RARB (0.65) | RARBRARARARGMCL1PPARG | |
| SCHEMBL5665946 | 0.79 | RARB (0.59) | RARBRARARARGBRS3PPARG | |
| SCHEMBL17487799 | 0.79 | RARB (0.42) | RARBRARARARGMCL1MPL | |
| SCHEMBL8472480 | 0.79 | CHRM5 (0.43) | LTB4R2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |