⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetamide SCHEMBL27598858 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL27678123 | 0.92 | LMNA (0.42) | — | |
| Trifluoroacetamide SCHEMBL142 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL27887692 | 0.89 | — | — | |
| Trifluoroacetamide SCHEMBL767845 | 0.89 | LMNA (0.57) | — | |
| Trifluoroacetamide SCHEMBL28553648 | 0.89 | LMNA (0.47) | — | |
| Trifluoroacetamide SCHEMBL6982843 | 0.88 | — | — | |
| Trifluoroacetamide SCHEMBL11793075 | 0.88 | — | — | |
| Trifluoroacetamide SCHEMBL11737106 | 0.88 | — | — | |
| Trifluoroacetamide SCHEMBL5638451 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1617718-A | N-aryl-N'-arylcycloalkyl-urea derivatives as MCH antagonists for the treatment of obesity | SCHERING CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| US-6414005-B1 | BRAIN DISORDERS; ALZHEIMER'S DISEASE; PARKINSON'S DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1043312-A1 | HETEROCYCLIC COMPOUNDS HAVING NOS INHIBITORY ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-10-11 | — | — | EP | disclosed |