Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739882 | 1.00 | FOLH1 (0.51) | FOLH1CCKBRADAMTS4ADAMTS5 | |
| SCHEMBL7740169 | 0.91 | HDAC1 (0.44) | — | |
| SCHEMBL7740174 | 0.91 | HDAC1 (0.44) | — | |
| SCHEMBL2249268 | 0.88 | ADAMTS5 (0.58) | FOLH1CCKBRADAMTS4ADAMTS5 | |
| SCHEMBL2245808 | 0.87 | ADAMTS5 (0.57) | FOLH1CCKBRADAMTS4ADAMTS5 | |
| SCHEMBL2250028 | 0.87 | ADAMTS5 (0.57) | FOLH1CCKBRADAMTS4ADAMTS5 | |
| SCHEMBL7740298 | 0.81 | ADAMTS5 (0.54) | FOLH1ADAMTS4ADAMTS5 | |
| SCHEMBL7742672 | 0.81 | ADAMTS5 (0.54) | FOLH1ADAMTS4ADAMTS5 | |
| SCHEMBL7740302 | 0.81 | ADAMTS5 (0.54) | FOLH1ADAMTS4ADAMTS5 | |
| SCHEMBL2244204 | 0.80 | L3MBTL1 (0.61) | FOLH1ADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |
| EP-0998475-A1 | NOVEL COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999005144-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-02-04 | — | — | WO | disclosed |