Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156764 | 0.97 | TSHR (0.33) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL30934742 | 0.89 | PHF8 (0.52) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL17619396 | 0.87 | LMNA (0.44) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL19447764 | 0.86 | — | — | |
| SCHEMBL25964897 | 0.82 | — | — | |
| SCHEMBL11605560 | 0.82 | — | — | |
| SCHEMBL24422510 | 0.80 | — | — | |
| SCHEMBL19819792 | 0.80 | — | — | |
| SCHEMBL13997980 | 0.80 | KDM4E (0.54) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL26448812 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417009-B1 | COUPLING LIPID | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY INSTITUTE (AU) | 2002-07-09 | — | — | US | disclosed |