Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739893 | 0.87 | KDM4E (0.36) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL464448 | 0.85 | — | — | |
| SCHEMBL11156764 | 0.84 | TSHR (0.33) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| Hydrochloric Acid SCHEMBL11654825 | 0.82 | — | — | |
| SCHEMBL3660629 | 0.79 | LMNA (0.63) | LMNAPOLBMCL1KDM4EKDM5C | |
| SCHEMBL2607890 | 0.78 | LMNA (0.46) | LMNAPOLBMCL1KDM4EKDM5C | |
| SCHEMBL30934742 | 0.78 | PHF8 (0.52) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL13129296 | 0.78 | LMNA (0.46) | LMNAPOLBMCL1KDM4EKDM5C | |
| SCHEMBL27368756 | 0.76 | LMNA (0.44) | LMNAPOLBMCL1ALDH1A1 | |
| SCHEMBL16281002 | 0.76 | ALDH1A1 (0.45) | LMNAPOLBMCL1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083726-A1 | Compositions and Methods for the Treatment of Parkinson Disease by the Selective Delivery of Oligonucleotide Molecules to Specific Neuron Types | PALOMO LIMITED (CY) | 2016-03-24 | — | — | US | disclosed |