Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508243 | 0.86 | CASP1 (0.61) | CASP1 | |
| SCHEMBL647066 | 0.81 | CASP1 (0.62) | CASP1 | |
| SCHEMBL12522512 | 0.81 | CASP1 (0.62) | CASP1 | |
| SCHEMBL7486694 | 0.80 | CASP1 (0.77) | CASP1 | |
| SCHEMBL648396 | 0.80 | CASP1 (0.61) | CASP1 | |
| SCHEMBL9696739 | 0.79 | CASP1 (0.59) | CASP1 | |
| SCHEMBL10888856 | 0.79 | CASP1 (0.59) | CASP1 | |
| SCHEMBL10884952 | 0.79 | CASP1 (0.59) | CASP1 | |
| SCHEMBL9241574 | 0.79 | CASP1 (0.59) | CASP1 | |
| SCHEMBL7337355 | 0.79 | CASP1 (0.59) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620782-B1 | Substituted 2-aminobenzamide caspase inhibitors and the use thereof | CYTOVIA, INC. | 2003-09-16 | — | — | US | disclosed |