Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122218 | 0.78 | PDE10A (0.49) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL10426653 | 0.78 | PDE10A (0.49) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL4920165 | 0.78 | ALDH1A1 (0.50) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL1011902 | 0.76 | ALDH1A1 (0.53) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL10666612 | 0.76 | PDE10A (0.47) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL15880740 | 0.76 | TDP1 (0.48) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL2381198 | 0.76 | PSMB8 (0.56) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| Potassium Ion SCHEMBL11302216 | 0.75 | TXNRD1 (0.53) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL11210857 | 0.73 | MEN1 (0.56) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 | |
| SCHEMBL4306213 | 0.73 | KDM4E (0.45) | PDE10ATXNRD1TXNRD3TXNRD2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020034657-A1 | Organic electroluminescence device | NEC CORPORATION. | 2002-03-21 | — | — | US | disclosed |