⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30763495 | 0.97 | CES1 (0.52) | — | |
| SCHEMBL22438671 | 0.85 | CES1 (0.59) | — | |
| SCHEMBL11139803 | 0.83 | CES2 (0.61) | — | |
| Butyric Acid SCHEMBL29244481 | 0.80 | FFAR3 (0.48) | — | |
| SCHEMBL28442996 | 0.78 | CES2 (0.61) | — | |
| SCHEMBL5026226 | 0.78 | — | — | |
| SCHEMBL16060357 | 0.76 | — | — | |
| SCHEMBL992042 | 0.76 | — | — | |
| SCHEMBL27694049 | 0.76 | — | — | |
| SCHEMBL2954775 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680317-A4 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | STANKO RONALD T M D (US) | 2000-12-06 | — | — | EP | claimed |
| EP-0680317-A1 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | Stanko, Ronald T., M.D. (US) | 1995-11-08 | — | — | EP | claimed |
| WO-1995011018-A1 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | UNIVERSITY OF PITTSBURGH MEDICAL CENTER (US) | 1995-04-27 | — | — | WO | claimed |
| US-5294641-A | Pyruvate | MONTEFIORE - UNIVERSITY HOSPITAL (US) | 1994-03-15 | — | — | US | claimed |
| CN-119215336-A | Disposable cervical HPV photodynamic automatic therapeutic apparatus | 北京英发光动技术有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-117623965-A | Crystal form of aminolevulinic acid hexyl hydrochloride, preparation method and pharmaceutical composition thereof | 广东精观生物医药科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-10901058-B2 | Chemical exchange saturation transfer (CEST) imaging of lactate (LATEST) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-01-26 | — | — | US | disclosed |
| CN-110352071-A | Lipidic nanoparticles mRNA vaccine | 库瑞瓦格股份公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-110018266-A | A kind of method of 48 kinds of amino acid of fast quantitative analysis | 广州市妇女儿童医疗中心 | 2019-07-16 | — | — | CN | disclosed |
| US-20170227619-A1 | Chemical Exchange Saturation Transfer (CEST) Imaging Of Lactate (LATEST) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-10 | — | — | US | disclosed |
| CN-105307722-A | Irradiation apparatus | PHOTOCURE ASA | 2016-02-03 | — | — | CN | disclosed |
| CN-104788565-A | Optimized Fc variants and methods for generation thereof | XENCOR INC | 2015-07-22 | — | — | CN | disclosed |
| CN-1705491-A | Optimized Fc variants and methods for their production | XENCOR INC (US) | 2005-12-07 | — | — | CN | disclosed |
| CN-1446104-A | Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications | IDEC PHARMA CORP (US) | 2003-10-01 | — | — | CN | disclosed |
| US-6417231-B1 | AQUEOUS COMPOSITION OF TRIPYRUVIN | TRI-PY INC. | 2002-07-09 | — | — | US | disclosed |
| EP-0680317-A4 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | STANKO RONALD T M D (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1998027977-A1 | DELIVERING THERAPEUTICALLY EFFECTIVE AMOUNTS OF PYRUVATE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1998-07-02 | — | — | WO | disclosed |
| EP-0680317-A1 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | Stanko, Ronald T., M.D. (US) | 1995-11-08 | — | — | EP | disclosed |
| WO-1995011018-A1 | METHOD FOR TREATING A MEDICAL PATIENT FOR CARDIAC TRAUMA | UNIVERSITY OF PITTSBURGH MEDICAL CENTER (US) | 1995-04-27 | — | — | WO | disclosed |
| US-5294641-A | Pyruvate | MONTEFIORE - UNIVERSITY HOSPITAL (US) | 1994-03-15 | — | — | US | disclosed |