Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.69 |
| ▸ | CTSK | P43235 | 10/20 | 0.60 |
| ▸ | CTSL | P07711 | 10/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165013 | 0.91 | CTSK (0.67) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL9393894 | 0.90 | CAPN1 (0.69) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL29577004 | 0.90 | CAPN1 (0.64) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL29678442 | 0.90 | CAPN1 (0.64) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL14148469 | 0.88 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL6482122 | 0.88 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL6276287 | 0.88 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL3492322 | 0.88 | TACR1 (0.61) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL6825534 | 0.86 | CAPN1 (0.74) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL931659 | 0.86 | CAPN1 (0.69) | CAPN1CTSKCTSLHTRA1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063350-A9 | CYSTEINE PROTEASE AND INHIBITORS FOR PREVENTION AND TREATMENT OF NEUROCYSTICEROCOSIS | UNIV GEORGIA RES FOUND (US) | 2002-06-13 | — | — | WO | disclosed |
| WO-2000063350-A2 | CYSTEINE PROTEASE AND INHIBITORS FOR PREVENTION AND TREATMENT OF NEUROCYSTICEROCOSIS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2000-10-26 | — | — | WO | disclosed |