Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742584 | 1.00 | CCKBR (0.46) | CCKBRFOLH1MMP8 | |
| SCHEMBL7740324 | 1.00 | CCKBR (0.46) | CCKBRFOLH1MMP8 | |
| SCHEMBL7741014 | 0.97 | FOLH1 (0.44) | CCKBRFOLH1 | |
| SCHEMBL7741016 | 0.97 | FOLH1 (0.44) | CCKBRFOLH1 | |
| SCHEMBL7740171 | 0.95 | MMP8 (0.46) | CCKBRMMP8 | |
| SCHEMBL7740175 | 0.95 | MMP8 (0.46) | CCKBRMMP8 | |
| SCHEMBL7742579 | 0.88 | POLB (0.40) | — | |
| SCHEMBL7742586 | 0.88 | POLB (0.40) | — | |
| SCHEMBL7734853 | 0.87 | HDAC1 (0.39) | — | |
| SCHEMBL7734857 | 0.87 | HDAC1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |