Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GPR39 | O43194 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419784 | 0.78 | PRKCQ (0.48) | CRHR1POLBCARM1PRMT6MAPT | |
| SCHEMBL25547612 | 0.78 | CRHR1 (0.41) | CRHR1POLBCARM1PRMT6IDH1 | |
| SCHEMBL632625 | 0.78 | POLB (0.60) | CRHR1POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4369018 | 0.78 | CRHR1 (0.52) | CRHR1MAPTHTTF10 | |
| SCHEMBL30288236 | 0.76 | KDM1A (0.46) | CRHR1POLBCARM1PRMT6ACHE | |
| SCHEMBL10055002 | 0.76 | CARM1 (0.57) | CRHR1CARM1PRMT6CYP3A4CYP2D6 | |
| SCHEMBL18434523 | 0.76 | CARM1 (0.57) | CRHR1CARM1PRMT6CYP3A4CYP2D6 | |
| SCHEMBL10055063 | 0.76 | CARM1 (0.57) | CRHR1CARM1PRMT6CYP3A4CYP2D6 | |
| SCHEMBL1722281 | 0.76 | CARM1 (0.57) | CRHR1CARM1PRMT6CYP3A4CYP2D6 | |
| SCHEMBL18901185 | 0.75 | DDB1 (0.46) | CRHR1POLBCARM1PRMT6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | claimed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | claimed |