Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | TRIM58 | Q8NG06 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722281 | 0.82 | CARM1 (0.57) | CRHR1CARM1PRMT6VCPSIGMAR1 | |
| SCHEMBL18434523 | 0.82 | CARM1 (0.57) | CRHR1CARM1PRMT6VCPSIGMAR1 | |
| SCHEMBL10055063 | 0.82 | CARM1 (0.57) | CRHR1CARM1PRMT6VCPSIGMAR1 | |
| SCHEMBL10055002 | 0.82 | CARM1 (0.57) | CRHR1CARM1PRMT6VCPSIGMAR1 | |
| SCHEMBL4369018 | 0.76 | CRHR1 (0.52) | CRHR1VCP | |
| SCHEMBL632625 | 0.76 | POLB (0.60) | CRHR1VCPPOLB | |
| SCHEMBL25547612 | 0.76 | CRHR1 (0.41) | CRHR1CARM1PRMT6POLBSIGMAR1 | |
| SCHEMBL1419784 | 0.76 | PRKCQ (0.48) | CRHR1CARM1PRMT6POLB | |
| SCHEMBL7740379 | 0.76 | CRHR1 (0.41) | CRHR1CARM1PRMT6POLBACHE | |
| SCHEMBL13438985 | 0.76 | SMYD3 (0.44) | KDM1ACRHR1CARM1PRMT6TRIM58 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | KDM1A 3310/4885MAOA 1187/4885CRHR1 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.