Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028758 | 0.82 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL678598 | 0.82 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL11608130 | 0.78 | KDM4E (0.55) | HIF1AEPAS1KDM4ECYP3A4LMNA | |
| SCHEMBL11608132 | 0.78 | KDM4E (0.55) | HIF1AEPAS1KDM4ECYP3A4LMNA | |
| SCHEMBL28448160 | 0.78 | KDM4E (0.50) | HIF1AEPAS1KDM4ECYP3A4LMNA | |
| SCHEMBL10572842 | 0.78 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL10572851 | 0.78 | KDM4E (0.59) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL15857617 | 0.76 | TRPA1 (0.56) | HIF1AEPAS1KDM4ECYP3A4LMNA | |
| SCHEMBL13790336 | 0.76 | RELA (0.81) | KDM4ECYP3A4LMNATP53TSHR | |
| SCHEMBL631998 | 0.76 | RELA (0.81) | KDM4ECYP3A4LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417306-B1 | ADDITION COPOLYMERIZATION OF MALEIMIDE AND METHACRYLIC ESTER; CHAIN TRANSFER WITH SULFUR COMPOUND; DISCOLORATION INHIBITION | NIPPON SHOKUBAI CO., LTD, (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-1108731-A2 | Transparent heat-resistant resin and production process therefor | Nippon Shokubai Co., Ltd. (JP) | 2001-06-20 | — | — | EP | disclosed |