SCHEMBL7740488

SCHEMBL7740488

Cc1cc(C)c(N(c2ccccc2)P(=O)(O)O)c(C)c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
ALDH1A1 P00352 6/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
ERAP1 Q9NZ08 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
ATM Q13315 1/20 0.30
FAAH O00519 1/20 0.30
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7742129 0.77 ESR2 (0.36) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL1470574 0.71 MAPT (0.44) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL2309806 0.71 MEN1 (0.48) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL8530739 0.71 MEN1 (0.48) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL5551256 0.71 MAPT (0.42) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL29883839 0.70 ALDH1A1 (0.37) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL29225323 0.70 SRC (0.45) MAPTALDH1A1HPGDPPARGPPARA
SCHEMBL28232231 0.70 ALDH1A1 (0.37) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL3145455 0.69 MAPT (0.42) MAPTALDH1A1MEN1KMT2AHTT
Hydrochloric Acid SCHEMBL27627985 0.69 MEN1 (0.46) MAPTALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414060-B1 ADDITION-CONDENSATION COPOLYMER ALBEMARLE CORPORATION 2002-07-02 US disclosed
EP-1067153-A1 Flame retardant polycarbonate-ABS polymer compositions ALBEMARLE CORPORATION (US) 2001-01-10 EP disclosed