SCHEMBL7740606

SCHEMBL7740606

O=C(O)C=C(C=Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 4/20 0.66
AKR1B1 P15121 4/20 0.66
CA12 O43570 4/20 0.66
CA7 P43166 4/20 0.66
CA9 Q16790 4/20 0.66
CA14 Q9ULX7 4/20 0.66
TYR P14679 3/20 0.66
CA1 P00915 3/20 0.66
CA2 P00918 3/20 0.66
PKM P14618 2/20 0.66
CA4 P22748 2/20 0.66
CA6 P23280 2/20 0.66
CA5A P35218 2/20 0.66
CA5B Q9Y2D0 2/20 0.66
ESR1 P03372 1/20 0.66
CA3 P07451 1/20 0.66
DPP4 P27487 1/20 0.66
HCAR2 Q8TDS4 1/20 0.66
ESR2 Q92731 1/20 0.66
GSK3B P49841 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL500728 0.85 HDAC3 (0.63) AKR1B10AKR1B1HCAR2F3CYP2D6
SCHEMBL29355034 0.85 HDAC3 (0.63) AKR1B10AKR1B1HCAR2F3CYP2D6
SCHEMBL29833146 0.85 HDAC3 (0.63) AKR1B10AKR1B1HCAR2F3CYP2D6
SCHEMBL8864888 0.84 FOS (0.59) AKR1B10AKR1B1CA12CA7CA9
SCHEMBL8864878 0.84 FOS (0.59) AKR1B10AKR1B1CA12CA7CA9
SCHEMBL25349366 0.84 CYP1B1 (0.49) AKR1B10AKR1B1CA12CA7CA9
SCHEMBL29540400 0.84 CYP1B1 (0.49) AKR1B10AKR1B1CA12CA7CA9
SCHEMBL8865328 0.84 CYP1A2 (0.58) AKR1B10AKR1B1CA12CA7CA9
Ammonia Solution, Strong SCHEMBL30095494 0.83 HDAC3 (0.61) AKR1B10AKR1B1HCAR2F3CYP2D6
Ammonia Solution, Strong SCHEMBL5466710 0.83 HDAC3 (0.61) AKR1B10AKR1B1HCAR2F3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6426175-B2 FORMING A GATE STACK LAYER ON A SUBSTRATE, PATTERNING THE STACK TO DEFINE A GATE AND TWO SPACERS, ONE OF THE SPACER AND GATE HAVE SPECIFIC WIDTH AND GATE HAS WIDTH THAT IS TWICE THE WIDTH OF ONE SPACE, FORMING SOURCE AND DRAIN REGIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-07-30 US disclosed
US-6420766-B1 Transistor having raised source and drain INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-07-16 US disclosed
US-20010021577-A1 METHOD FOR FORMING SIDEWALL SPACERS USING FREQUENCY DOUBLING HYBRID RESIST AND DEVICE FORMED THEREBY BROWN JEFFREY S (US) 2001-09-13 US disclosed
US-6255178-B1 Method for forming transistors with raised source and drains and device formed thereby INTERNATIONAL BUSINESS MACHINES CORP. 2001-07-03 US disclosed
US-6245488-B1 EXPOSING RESIST TO ACTINIC RADIATION AT AN INTERMEDIATE ENERGY FIRST THROUGH A MASK HAVING BLOCKING FEATURE SHAPES THEN THROUGH A SECOND MASK HAVING TRIM SHAPES WHICH LINK THE FEATURES, DEVELOPING AND TRIMMING THE LINKING PORTION INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-06-12 US disclosed
US-20010003034-A1 FABRICATION OF A HIGH DENSITY LONG CHANNEL DRAM GATE WITH OR WITHOUT A GROOVED GATE INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-06-07 US disclosed
US-6232639-B1 Method and structure to reduce latch-up using edge implants INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-05-15 US disclosed
US-6218704-B1 ESD protection structure and method INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-04-17 US disclosed
US-6210866-B1 Method for forming features using self-trimming by selective etch and device formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-04-03 US disclosed
US-6147394-A Method of photolithographically defining three regions with one mask step and self aligned isolation structure formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2000-11-14 US disclosed
US-6100013-A Method for forming transistors with raised source and drains and device formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2000-08-08 US disclosed
US-6033949-A Method and structure to reduce latch-up using edge implants INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2000-03-07 US disclosed
US-6014422-A Method for varying x-ray hybrid resist space dimensions INTERNAITONAL BUSINESS MACHINES CORPORATION (US) 2000-01-11 US disclosed
US-6007968-A Method for forming features using frequency doubling hybrid resist and device formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-12-28 US disclosed
US-5976768-A Method for forming sidewall spacers using frequency doubling hybrid resist and device formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-11-02 US disclosed
US-5972570-A Method of photolithographically defining three regions with one mask step and self aligned isolation structure formed thereby INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-10-26 US disclosed
US-5939767-A Structure and process for buried diode formation in CMOS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-08-17 US disclosed
US-5882967-A Process for buried diode formation in CMOS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-03-16 US disclosed
US-5861330-A FORMING IMPLANTS WITH HYBRID RESISTS WHICH DO NOT REQUIRE ADDITIONAL MASKING STEPS AT THE WELL EDGES; IMPLANTS REDUCE THE LIFETIME OF MINORITY CARRIERS IN THE PARASITIC TRANSISTOR, REDUCING GAIN OF THE PARASITIC TRANSISTOR INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-01-19 US disclosed