Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740373 | 0.88 | KMT2A (0.43) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7739561 | 0.86 | KDM4E (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7734586 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7734712 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7742335 | 0.83 | MAPT (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7734708 | 0.82 | KMT2A (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7740742 | 0.77 | KMT2A (0.50) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7739350 | 0.73 | KDM4E (0.43) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7734611 | 0.73 | POLB (0.40) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7734767 | 0.73 | KDM4E (0.40) | ALDH1A1LMNASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420410-B1 | ADMINISTERING N,N'-SUBSTITUTED BENZIMIDAZOL-2-ONES TO INDUCE APOPTOSIS IN NEOPLASTIC CELLS BUT NOT NORMAL CELLS; ANTICANCER, ANTITUMOR AGENT | CELL PATHWAYS, INC. | 2002-07-16 | — | — | US | disclosed |