Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11893183 | 0.96 | NFE2L2 (0.60) | NFE2L2L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL7732352 | 0.89 | HRH2 (0.49) | NFE2L2L3MBTL1KDM4EHRH2HRH1 | |
| SCHEMBL8363893 | 0.86 | NFE2L2 (0.45) | NFE2L2L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL7737448 | 0.84 | PARP10 (0.66) | L3MBTL1GAAMEN1KMT2APARP15 | |
| SCHEMBL7316232 | 0.82 | NFE2L2 (0.62) | NFE2L2L3MBTL1MEN1KMT2APARP15 | |
| SCHEMBL8363827 | 0.82 | GAA (0.54) | L3MBTL1GAAMEN1KMT2AMAPT | |
| SCHEMBL7733823 | 0.81 | PARP15 (0.66) | L3MBTL1GAAMEN1KMT2APARP15 | |
| SCHEMBL7321013 | 0.81 | NFE2L2 (0.60) | NFE2L2MEN1KMT2APARP15PARP10 | |
| SCHEMBL6958286 | 0.81 | PARP10 (0.72) | L3MBTL1GAAMEN1KMT2APARP15 | |
| SCHEMBL7733935 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1HRH2HRH1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |