Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.66 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.66 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733823 | 0.97 | PARP15 (0.66) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL4117982 | 0.95 | PARP10 (0.71) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL6958286 | 0.94 | PARP10 (0.72) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL2087536 | 0.89 | PARP15 (0.70) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL20067679 | 0.87 | TDP1 (0.58) | PARP10PARP15PARP2L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL15538060 | 0.86 | TDP1 (0.61) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL7740744 | 0.84 | NFE2L2 (0.56) | PARP10PARP15L3MBTL1MAPTLMNA | |
| SCHEMBL17150475 | 0.82 | PARP15 (0.56) | PARP10PARP15PARP2L3MBTL1MAPT | |
| SCHEMBL12420703 | 0.81 | PARP10 (0.73) | PARP10PARP15PARP2FFAR1MEN1 | |
| SCHEMBL16803726 | 0.80 | PARP15 (0.43) | PARP10PARP15PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |