SCHEMBL774078

SCHEMBL774078

N=CC(=N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3991502 0.70
SCHEMBL23975303 0.69
SCHEMBL1041578 0.67
SCHEMBL294544 0.67
SCHEMBL3765911 0.67
SCHEMBL24157570 0.67
SCHEMBL288735 0.67
SCHEMBL8463208 0.67 ALDH1A1 (0.47)
SCHEMBL1551311 0.67
Guanidine SCHEMBL165720 0.65 NOS2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4101845-A1 METHOD FOR PRODUCING CARBOXYLATE COMPOUND AND METHOD FOR PRODUCING AMIDATE COMPOUND Koei Chemical Company, Limited (JP) 2022-12-14 EP disclosed
US-8637434-B2 System for photolithographic synthesis of polymer arrays AFFYMETRIX, INC. (US) 2014-01-28 US disclosed
US-20130059763-A1 System for photolithographic synthesis of polymer arrays AFFYMETRIX, INC. (US) 2013-03-07 US disclosed
WO-2013018735-A1 AMIDINE COMPOUND OR SALT THEREOF 大正製薬株式会社 (JP) 2013-02-07 WO disclosed
US-8309496-B2 Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings AFFYMETRIX, INC. (US) 2012-11-13 US disclosed
US-20120071361-A1 Substrate Preparation Process AFFYMETRIX, INC. (US) 2012-03-22 US disclosed
US-8067578-B2 Substrate preparation process AFFYMETRIX, INC. (US) 2011-11-29 US disclosed
EP-2316835-A1 Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases Vertex Pharmceuticals Incorporated (US) 2011-05-04 EP disclosed
WO-2011014515-A1 2, 7 -NAPHTHYRIDIN- 1 -ONE DERIVATIVES AS SYK KINASE INHIBITORS IRM LLC (BM) 2011-02-03 WO disclosed
US-20100331217-A1 SUBSTRATE PREPARATION PROCESS AFFYMETRIX, INC. (US) 2010-12-30 US disclosed
US-20060008840-A1 Substrate preparation process AFFYMETRIX, INC. (US) 2006-01-12 US disclosed
US-20050181396-A1 Substrate preparation process AFFYMETRIX, INC. (US) 2005-08-18 US disclosed
US-20050181431-A1 Flow device for preparation of microarrays comprising positionally distinct polymer sequences; high throughput assay AFFYMETRIX, INC. (US) 2005-08-18 US disclosed
EP-0950112-A4 PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS AFFYMETRIX INC (US) 2004-12-15 EP disclosed
US-6706875-B1 PREPARING SOLID SUBSTRATE FOR FORMING POLYMER SEQUENCES THEREON BY PROVIDING FUNCTIONAL GROUPS ON SURFACE OF SUBSTRATE AND COUPLING MONOMERS INCLUDING LIPOPHILIC PHOSPHORAMIDITE GROUPS TO FUNCTIONAL GROUPS AFFYEMTRIX, INC. 2004-03-16 US disclosed
US-6307042-B1 GENERATING NUCLEOTIDE SEQUENCES; PROVIDE SUBSTRATE WAFERS, REMOVE PROTECTED GROUPS, TRANSFER SUBSTRATE WAFERS TO COUPLING STATION, TRANSFER SUBSTRATE WAFER TO ACTIVATION STATION, ANALYZE POLYMER LAYOUTS AFFYMETRIX, INC. 2001-10-23 US disclosed
EP-0950112-A1 PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS Affymetrix, Inc. (a California Corporation) (US) 1999-10-20 EP disclosed
US-5959098-A ACTIVATING AND COUPLING MONOMERS IN DIFFERENT SELECTED ZONES OF SUBSTRATE FORMING DIFFERENT SEQUENCES IN DIFFERENT AREAS; ACTIVATING BY DIRECTING RADIATION AT SURFACE OF SUBSTRATE WITH FUNCTIONAL GROUPS PROTECTED BY PHOTOLABILE GROUPS AFFYMETRIX, INC. (US) 1999-09-28 US disclosed
WO-1997039151-A1 PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS AFFYMETRIX, INC. (US) 1997-10-23 WO disclosed
US-4644006-A ANTIULCER AGENTS BRISTOL-MYERS COMPANY (US) 1987-02-17 US disclosed