Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 8/20 | 0.44 |
| ▸ | CMA1 | P23946 | 7/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740994 | 1.00 | CTSG (0.44) | CTSGCMA1PRSS1CTRB1SLC1A1 | |
| SCHEMBL7740986 | 0.92 | CTSG (0.40) | CTSGCMA1PRSS1CTRB1 | |
| SCHEMBL7740982 | 0.92 | CTSG (0.40) | CTSGCMA1PRSS1CTRB1 | |
| SCHEMBL7741230 | 0.92 | MEN1 (0.41) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7741223 | 0.92 | MEN1 (0.41) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7742770 | 0.91 | MEN1 (0.42) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7742759 | 0.91 | MEN1 (0.42) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7740159 | 0.84 | MEN1 (0.39) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7740158 | 0.84 | MEN1 (0.39) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL6304829 | 0.84 | MEN1 (0.41) | CTSGCMA1PRSS1CTRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |