Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745717 | 0.79 | LRRK2 (0.54) | MAPTALDH1A1NPC1GAARAB9A | |
| SCHEMBL6669676 | 0.75 | LRRK2 (0.38) | CYP1A2MAPTALDH1A1NPC1GAA | |
| SCHEMBL6669681 | 0.75 | LRRK2 (0.38) | CYP1A2MAPTALDH1A1NPC1GAA | |
| SCHEMBL21994233 | 0.72 | CYP1A2 (0.51) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL6246169 | 0.72 | ALDH1A1 (0.43) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL6246167 | 0.72 | ALDH1A1 (0.43) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL29759335 | 0.66 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL22806019 | 0.66 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL2493976 | 0.66 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 | |
| SCHEMBL20218242 | 0.66 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2TNKS2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |