Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746216 | 0.89 | MAPT (0.38) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL8363907 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7745971 | 0.86 | TP53 (0.34) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7746104 | 0.85 | TSHR (0.35) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7746108 | 0.85 | TSHR (0.33) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7741368 | 0.83 | RAB9A (0.43) | SMN1; SMN2TP53RAB9ANPC1POLB | |
| SCHEMBL7741673 | 0.78 | CYP3A4 (0.43) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7745795 | 0.76 | MEN1 (0.43) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL7745784 | 0.75 | CYP3A4 (0.40) | SMN1; SMN2TP53RAB9ANPC1TSHR | |
| SCHEMBL8363973 | 0.74 | ALDH1A1 (0.38) | SMN1; SMN2TP53TSHRPTK2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |