Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829825 | 0.85 | TDP1 (0.49) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL11140840 | 0.84 | POLB (0.54) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL15428898 | 0.81 | POLB (0.44) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL16407595 | 0.81 | LTA4H (0.45) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL27244263 | 0.81 | POLB (0.44) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL7745491 | 0.81 | POLB (0.47) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL2597681 | 0.81 | POLB (0.44) | POLBTDP1LTA4HEPHX2MEN1 | |
| SCHEMBL914851 | 0.80 | POLB (0.47) | POLBTDP1MEN1KMT2ACA1 | |
| SCHEMBL7526320 | 0.80 | NPSR1 (0.41) | POLBLTA4HEPHX2MEN1KMT2A | |
| SCHEMBL9407115 | 0.79 | TDP1 (0.45) | POLBTDP1LTA4HEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5569664-A | AGRICULTURAL INSECTICIDES | FMC CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |