SCHEMBL7745491

SCHEMBL7745491

CCOP(=O)(OCC)c1ccc(CO)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
LTA4H P09960 2/20 0.42
EPHX2 P34913 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
HTR2A P28223 1/20 0.37
HTR2B P41595 1/20 0.37
PPARD Q03181 2/20 0.36
ACHE P22303 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829825 0.85 TDP1 (0.49) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL11140840 0.84 POLB (0.54) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL17714648 0.82 CYP4A11 (0.46) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL2597681 0.81 POLB (0.44) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL15428898 0.81 POLB (0.44) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL7741344 0.81 POLB (0.44) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL16407595 0.81 LTA4H (0.45) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL27244263 0.81 POLB (0.44) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL2985030 0.80 ALDH1A1 (0.47) POLBLTA4HEPHX2MEN1KMT2A
SCHEMBL914688 0.80 MEN1 (0.47) POLBLTA4HEPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8062816-B2 Phosphonate hole blocking layer photoconductors XEROX CORPORATION (US) 2011-11-22 US disclosed
US-8053151-B2 Phosphonate containing photoconductors XEROX CORPORATION (US) 2011-11-08 US disclosed
US-20090325091-A1 PHOSPHONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US disclosed
US-20090297967-A1 PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-03 US disclosed
US-6774134-B2 FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION BRISTOL-MYERS SQUIBB COMPANY 2004-08-10 US disclosed
US-6774134-B2 FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION BRISTOL-MYERS SQUIBB COMPANY 2004-08-10 US disclosed
US-5639763-A FOR AGRICULTURAL APPLICATIONS FMC CORPORATION (US) 1997-06-17 US disclosed
US-5569664-A AGRICULTURAL INSECTICIDES FMC CORPORATION (US) 1996-10-29 US disclosed