Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683489 | 0.90 | HPGD (0.68) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4678036 | 0.76 | TRPA1 (0.56) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4685394 | 0.74 | SMN1; SMN2 (0.54) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4679156 | 0.74 | LMNA (0.62) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4679490 | 0.72 | HPGD (1.00) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4678844 | 0.72 | HPGD (0.70) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5782189 | 0.71 | KMT2A (0.54) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| Hydrazine SCHEMBL6342964 | 0.70 | KMT2A (0.61) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28863365 | 0.70 | MEN1 (0.53) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12156864 | 0.70 | KMT2A (0.53) | MAPTHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | disclosed |