Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.59 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181465 | 0.98 | HDAC1 (0.62) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL30544993 | 0.98 | HDAC1 (0.62) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL27889590 | 0.96 | HDAC1 (0.60) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL9504571 | 0.96 | HDAC1 (0.60) | HDAC1HDAC6P4HA1P4HTMMIF | |
| Benzoic Acid SCHEMBL28287250 | 0.90 | HDAC1 (0.55) | HDAC1HDAC6P4HA1P4HTMMIF | |
| Propanol SCHEMBL28719045 | 0.87 | MAPT (0.53) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL7528433 | 0.84 | KDM4E (0.58) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL30425369 | 0.83 | P4HA1 (0.55) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL13320208 | 0.83 | P4HA1 (0.55) | HDAC1HDAC6P4HA1P4HTMMIF | |
| SCHEMBL4400941 | 0.82 | HDAC1 (0.64) | HDAC1HDAC6ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001029003-A1 | PROCESS FOR THE PREPARATION OF 1-(6-METHYLPYRIDIN-3-YL)-2-(4-METHYLTHIOPHENYL)-ETHANONE AND ITS USE IN THE SYNTHESIS OF DIARYLPYRIDINES | ZAMBON GROUP S.P.A. (IT) | 2001-04-26 | — | — | WO | disclosed |