Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | OSBP | P22059 | 1/20 | 0.70 |
| ▸ | RORC | P51449 | 1/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.70 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.64 |
| ▸ | POLA1 | P09884 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284415 | 0.94 | USP2 (0.69) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL1243707 | 0.91 | USP2 (0.66) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL10929500 | 0.90 | USP2 (0.65) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL10930823 | 0.90 | USP2 (0.65) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL10929495 | 0.90 | USP2 (0.65) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL3977940 | 0.89 | CYP46A1 (0.64) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL8605712 | 0.89 | CYP46A1 (0.64) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL3508152 | 0.89 | CYP46A1 (0.71) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL103515 | 0.89 | USP2 (0.74) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL2185461 | 0.89 | USP2 (0.74) | USP2CYP46A1LMNAABCB1OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423702-B1 | PROCESS FOR THE HYDROXYLATION OF AN ACYCLIC OR CYCLIC METHYLENE RADICAL IN THE ALLYLIC POSITION, PHARMACEUTICAL COMPOSITION CONTAINING HYDROXYCHOLESTEROL DERIVATIVES AND UTILIZATION OF SUCH COMPOSITIONS FOR THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-07-23 | — | — | US | disclosed |
| EP-0540649-A1 | METHOD FOR HYDROXYLATION OF A CYCLIC OR ACYCLIC METHYLENE RADICAL IN THE ALLYLIC POSITION, PHARMACEUTICAL COMPOSITION CONTAINING HYDROXYCHOLESTEROL DERIVATIVES AND UTILISATION OF SUCH COMPOSITIONS FOR THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001803-A1 | METHOD FOR HYDROXYLATION OF A CYCLIC OR ACYCLIC METHYLENE RADICAL IN THE ALLYLIC POSITION, PHARMACEUTICAL COMPOSITION CONTAINING HYDROXYCHOLESTEROL DERIVATIVES AND UTILISATION OF SUCH COMPOSITIONS FOR THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1992-02-06 | — | — | WO | disclosed |