SCHEMBL2185461

SCHEMBL2185461

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(O)(O)CC[C@]4(C)[C@@H]3CC[C@]12C

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.74
CYP46A1 Q9Y6A2 2/20 0.74
LMNA P02545 1/20 0.74
ABCB1 P08183 1/20 0.74
OSBP P22059 1/20 0.74
RORC P51449 1/20 0.74
OSBP2 Q969R2 1/20 0.74
GRIN1 Q05586 15/20 0.68
GRIN2B Q13224 15/20 0.68
GRIN2A Q12879 13/20 0.67
POLA1 P09884 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103515 1.00 USP2 (0.74) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL932623 1.00 USP2 (0.74) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4961477 0.92 GRIN1 (0.80) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL5935410 0.92 GRIN1 (0.80) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL21822074 0.91 OSBP (0.75) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10887781 0.90 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8930167 0.90 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18529717 0.90 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL720338 0.90 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10943687 0.90 USP2 (0.71) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117587045-B Veratric cholesterol 22 (R) -hydroxylase VnCYP B27 gene and application thereof 云南农业大学 2024-04-16 CN claimed
CN-117587045-A Veratric cholesterol 22 (R) -hydroxylase VnCYP90B27 gene and application thereof 云南农业大学 2024-02-23 CN claimed
CN-116322710-A Pharmaceutical composition comprising gamma-cyclodextrin polymer and use thereof 株式会社雷纳图斯 2023-06-23 CN claimed
WO-2019176857-A1 PROMOTER FOR INDUCING DIFFERENTIATION OF INSULIN-PRODUCING CELLS 味の素株式会社 2019-09-19 WO claimed
WO-2006007528-A9 LXR/RXR-RELATED METHODS AND COMPOSITIONS UNIV COLUMBIA (US) 2006-04-27 WO claimed
WO-2006007528-A2 LXR/RXR-RELATED METHODS AND COMPOSITIONS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-01-19 WO claimed
JP-2002506817-A 2002-03-05 JP claimed
EP-1063989-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-01-03 EP claimed
WO-1999047136-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1999-09-23 WO claimed
EP-4638461-A1 DUAL LIPID STRUCTURES Turn Biotechnologies, Inc. (US) 2025-10-29 EP disclosed
EP-4638465-A1 IONIZABLE LIPIDS WITH DEGRADABLE HEAD Turn Biotechnologies, Inc. (US) 2025-10-29 EP disclosed
US-20250305010-A1 LIPID COMPOSITIONS AND METHODS OF PRODUCING SAME WILK TECHNOLOGIES INTERNATIONAL LTD. (IL) 2025-10-02 US disclosed
US-12171909-B2 Implants having a drug load of an oxysterol and methods of use WARSAW ORTHOPEDIC, INC. (US) 2024-12-24 US disclosed
WO-2024138034-A1 IONIZABLE LIPIDS WITH DEGRADABLE HEAD TURN BIOTECHNOLOGIES, INC. (US) 2024-06-27 WO disclosed
US-20030153541-A1 Novel anticholesterol compositions and method for using same ANAGEN THERAPEUTICS, INC. 2003-08-14 US disclosed
WO-2001083506-A1 HUMAN ABC1 PROMOTER AND ASSAYS BASED THEREON THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2001-11-08 WO disclosed
EP-1063989-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-01-03 EP disclosed
EP-1063989-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-01-03 EP disclosed
WO-1999047136-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1999-09-23 WO disclosed
WO-1999047136-A1 PREVENTION AND TREATMENT OF ADHESIONS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1999-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12171909-B2 Implants having a drug load of an oxysterol and methods of use SOST, CYP17A1, HSD17B7 USP2 900/4885CYP46A1 8/4885LMNA 1681/4885
US-20030153541-A1 Novel anticholesterol compositions and method for using same CYP46A1, NR1H4, NR1H3 USP2 3773/4885CYP46A1 1/4885LMNA 1254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.