Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637953 | 0.86 | MTNR1A (0.60) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL11418268 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15757946 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8293076 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BNPC1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5424364 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BNPC1ALDH1A1GAA | |
| SCHEMBL8437389 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BNPC1ALDH1A1GAA | |
| SCHEMBL490458 | 0.76 | HSD17B10 (0.55) | MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL491098 | 0.76 | POLB (0.54) | NPC1ALDH1A1RAB9ATSHR | |
| SCHEMBL4508144 | 0.75 | CYP4F2 (0.49) | MTNR1AMTNR1BNPC1ALDH1A1GAA | |
| SCHEMBL11893016 | 0.75 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |